WHO "essential medicine" N-acetylcysteine ("NAC") is the standard treatment for #paracetamol overdose; it replenishes depleted glutathione reserves, which conjugate N-acetyl-p-benzoquinone imine (“NAPQI”), the toxic metabolite. It’s also a mucolytic, decreases the effects of alcohol, and sometimes helps with mental disorders. #drugs #toxicology #medicine
on 02026-04-22#paracetamol is safer than #ibuprofen, but perverse incentives make it hard to find that out. #Dynomight #drugs #NSAIDs #medicine
on 02026-04-22previous #medical #paper calling for caution around #paracetamol use during pregnancy due to risks of #autism, etc.
on 02025-09-10#medical #paper finding no increase in #autism or #ADHD due to #paracetamol use during pregnancy — when controlled for siblings. What does this mean?
on 02025-09-10